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MCAS as a cause for EDS? Is it a cause or an exacerbating factor?
There are many studies and clinical data pointing to the idea that Mast Cell Activation causes a lot of the symptoms related to hEDS/HSD. Gastrointestinal symptoms, Joint Pain, Skin reactions, Brain fog all can find its roots in MCAS.
Here are just a couple of sites describing this phenomena.
https://www.ifm.org/news-insights/mast-cell-activation-syndrome/
https://youtu.be/0KxDYYsDcQQ?si=NoUISm5DbMzyjezN